Matrix information:
(Help) ADAN-name: 1FYN2.PDB Scoring matrix: 1FYN2_mat Uniprot code: P06241 Genome source: Homo sapiens Wild-type ligand: PPAYPPPPVP Foldx wt ligand score: 6.58 Foldx random average score for Homo sapiens: 13.805 Available information for P06241 in MINT (Nov 2008): Nš of interacting proteins: 29 Proteins belonging to other specie: 8 Nš of interactions described: 52 Interactions with other species: 15
Genome scanning information:
Subcellular location: True Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 40317 Total fragments: 18210495 Proteins after random average filtering: 40296 Total fragments: 9418678 Proteins after disorder filtering: 30246 Total fragments: 1048615 Proteins after pattern filtering: 21870 Total fragments: 367212 Proteins after MINT filtering: 15 Total fragments: 599
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
PPAYPPPPVP |
6.58
|
-10.76 |
0.00 |
Best peptides |
RPKGFPPDNM |
0.00
|
-10.43 |
0.33 |
|
|
|
|
|
Interactors |
|
|
|
|
P54253 |
APGLITPGSP |
6.46
|
-10.61 |
0.15 |
|
TPGSPPPAQQ |
6.59
|
-9.29 |
1.47 |
|
TPQPGTPVSP |
7.27
|
-10.20 |
0.56 |
P11137 |
VPGIDLPKEP |
5.96
|
-11.75 |
-0.99 |
|
LPKEPPTPKE |
6.75
|
-9.92 |
0.84 |
|
TPGTPPSYSS |
7.92
|
-7.63 |
3.13 |
O15117 |
KPVGPKPINL |
4.78
|
-9.64 |
1.12 |
|
TPKQKPLPPL |
6.38
|
-10.54 |
0.22 |
|
FTLGPPPPKP |
6.55
|
-10.55 |
0.21 |
P22681 |
RPIPKVPVSA |
6.26
|
-10.82 |
-0.06 |
|
KPLPVPPTLR |
6.36
|
-9.75 |
1.01 |
|
VPKLPPGEQC |
6.38
|
-11.14 |
-0.38 |
Q13177 |
FPSGTPALNA |
4.67
|
-9.50 |
1.26 |
|
PPAPPVRMSS |
9.78
|
-8.71 |
2.05 |
|
KPPAPPVRMS |
10.00
|
-8.28 |
2.48 |
Q13283 |
RPESKPESQI |
6.33
|
-11.72 |
-0.96 |
|
GPGGPRGGLG |
7.14
|
-7.06 |
3.70 |
|
PPQRGPRPIR |
7.37
|
-10.36 |
0.40 |
P25445 |
FCHKPCPPGE |
9.96
|
-7.81 |
2.95 |
|
KPCPPGERKA |
11.17
|
-6.53 |
4.23 |
|
GQFCHKPCPP |
11.52
|
-6.81 |
3.95 |
Q13444 |
PPRKPLPADP |
6.47
|
-12.98 |
-2.22 |
|
RPAPPPPTVS |
6.51
|
-11.68 |
-0.92 |
|
GPAKPPPPRK |
6.74
|
-10.61 |
0.15 |
P42768 |
TPRGPPPPGR |
3.79
|
-11.63 |
-0.87 |
|
RRGGLPPLPL |
5.08
|
-10.79 |
-0.03 |
|
VPLGIAPPPP |
5.22
|
-11.11 |
-0.35 |
P16333 |
KPSVPDSASP |
10.20
|
-6.99 |
3.77 |
|
KVKRKPSVPD |
10.51
|
-9.39 |
1.37 |
|
KRKPSVPDSA |
10.68
|
-8.63 |
2.13 |
Q9Y5K6 |
KPKKPPPPAK |
5.13
|
-12.55 |
-1.79 |
|
RPEKPVPPPP |
5.56
|
-13.84 |
-3.08 |
|
FPKPKKPPPP |
5.85
|
-13.26 |
-2.50 |
P29353 |
LPVGQPVGGD |
5.69
|
-9.29 |
1.47 |
|
FPGKEPPLGG |
5.85
|
-9.98 |
0.78 |
|
MPESGPLPLL |
7.05
|
-9.70 |
1.06 |
P12931 |
FPASQTPSKP |
7.39
|
-11.95 |
-1.19 |
|
TPSKPASADG |
10.72
|
-6.70 |
4.06 |
|
PASQTPSKPA |
11.67
|
-6.36 |
4.40 |
P06729 |
RPRVQPKPPH |
4.52
|
-9.98 |
0.78 |
|
LPRPRVQPKP |
6.54
|
-13.84 |
-3.08 |
|
PPLPRPRVQP |
6.80
|
-10.25 |
0.51 |
P35968 |
GPQPLPIHVG |
8.76
|
-7.48 |
3.28 |
|