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Matrix information:
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ADAN-name: 1EFN2.PDB
Scoring matrix: 1EFN2_mat
Uniprot code: P06241
Genome source: Homo sapiens
Wild-type ligand: RPQVPLRPMTY
Foldx wt ligand score: 1.95
Foldx random average score for Homo sapiens: 8.202 Available information for P06241 in MINT (Nov 2008):
Nš of interacting proteins: 29
Proteins belonging to other specie: 8
Nš of interactions described: 52
Interactions with other species: 15
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18170188
Proteins after random average filtering: 40287
Total fragments: 8617287
Proteins after disorder filtering: 28611
Total fragments: 678715
Proteins after pattern filtering: 21314
Total fragments: 278064
Proteins after MINT filtering: 15
Total fragments: 489
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RPQVPLRPMTY |
1.95
|
-8.98 |
0.00 |
| Best peptides |
MPRMPHRRRHF |
0.00
|
-9.22 |
-0.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P54253 |
TASPPAIPVHL |
6.05
|
-6.46 |
2.52 |
|
PGNPGGRGHGG |
6.11
|
-5.73 |
3.25 |
|
LPGNPGGRGHG |
6.22
|
-6.87 |
2.11 |
| P11137 |
TPGTPSYPRTP |
5.32
|
-6.99 |
1.99 |
|
YPRTPHTPGTP |
5.37
|
-6.05 |
2.93 |
|
TPHTPGTPKSA |
5.78
|
-5.86 |
3.12 |
| O15117 |
PPPKPNRPPNV |
2.00
|
-11.63 |
-2.65 |
|
GPLKPAREDSE |
2.40
|
-9.86 |
-0.88 |
|
VPSLPPRNIKP |
2.67
|
-10.90 |
-1.92 |
| P22681 |
PPPPPDRPYSV |
2.83
|
-11.87 |
-2.89 |
|
AESRPQRRPLP |
3.54
|
-9.85 |
-0.87 |
|
RPDVPRLGSTF |
3.98
|
-8.62 |
0.36 |
| Q13177 |
PPAPPVRMSST |
2.81
|
-10.95 |
-1.97 |
|
KPPAPPVRMSS |
5.32
|
-7.45 |
1.53 |
|
PAPPVRMSSTI |
6.91
|
-5.19 |
3.79 |
| Q13283 |
PPQRGPRPIRE |
4.22
|
-8.50 |
0.48 |
|
VPASQPRPESK |
5.49
|
-8.17 |
0.81 |
|
RGPGGPRGGLG |
5.67
|
-5.46 |
3.52 |
| P25445 |
KPCPPGERKAR |
5.43
|
-7.59 |
1.39 |
|
PCPPGERKARD |
5.90
|
-7.33 |
1.65 |
|
FCHKPCPPGER |
6.95
|
-5.35 |
3.63 |
| Q13444 |
RPGPPQRALLA |
2.45
|
-11.24 |
-2.26 |
|
PLVVPSRPAPP |
3.38
|
-10.59 |
-1.61 |
|
AKPPPPRKPLP |
4.38
|
-10.11 |
-1.13 |
| P42768 |
PPPPPSRGGNQ |
2.82
|
-10.60 |
-1.62 |
|
GPPPPGRGGPP |
3.11
|
-9.01 |
-0.03 |
|
PPLPPALVPAG |
4.87
|
-7.28 |
1.70 |
| P16333 |
KPSVPDSASPA |
5.43
|
-7.71 |
1.27 |
|
EPSPPQCDYIR |
6.06
|
-6.04 |
2.94 |
|
VKRKPSVPDSA |
6.17
|
-6.19 |
2.79 |
| Q9Y5K6 |
RPKMPGRRLPG |
0.98
|
-12.88 |
-3.90 |
|
YPKRPEKPVPP |
4.24
|
-8.04 |
0.94 |
|
GTVYPKRPEKP |
4.42
|
-7.76 |
1.22 |
| P29353 |
PPPCPGRELFD |
2.63
|
-11.00 |
-2.02 |
|
RRKPCSRPLSS |
4.93
|
-8.17 |
0.81 |
|
MPPPPPCPGRE |
5.29
|
-8.57 |
0.41 |
| P12931 |
TPSKPASADGH |
5.44
|
-6.45 |
2.53 |
|
ASQTPSKPASA |
6.99
|
-5.33 |
3.65 |
| P06729 |
PPLPRPRVQPK |
2.88
|
-10.87 |
-1.89 |
|
PPPPGHRVQHQ |
4.18
|
-9.62 |
-0.64 |
|
KGPPLPRPRVQ |
4.29
|
-10.15 |
-1.17 |
| P35968 |
GPQPLPIHVGE |
6.19
|
-6.59 |
2.39 |
|
PQPLPIHVGEL |
6.85
|
-5.75 |
3.23 |
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