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Matrix information:
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ADAN-name: 1AZE2.PDB
Scoring matrix: 1AZE2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 4.05
Foldx random average score for Homo sapiens: 9.188 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
Total fragments: 13515704
Proteins after random average filtering: 32213
Total fragments: 7347589
Proteins after disorder filtering: 24002
Total fragments: 604923
Proteins after pattern filtering: 17322
Total fragments: 187015
Proteins after MINT filtering: 8
Total fragments: 264
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPPPVPPRRR |
4.05
|
-9.29 |
0.00 |
| Best peptides |
DWFPMPRMGR |
0.00
|
-9.72 |
-0.43 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
KKISPPTPKP |
6.09
|
-6.32 |
2.97 |
|
PRPPRPLPVA |
6.30
|
-6.98 |
2.31 |
|
PKPPKPTTVA |
6.37
|
-6.51 |
2.78 |
| Q07889 |
VPPPVPPRRR |
4.05
|
-10.52 |
-1.23 |
|
SPPAIPPRQP |
4.14
|
-8.19 |
1.10 |
|
AGPPVPPRQS |
4.39
|
-9.31 |
-0.02 |
| Q9UKW4 |
PCVPKPVDYS |
6.52
|
-6.11 |
3.18 |
|
PCPCVPKPVD |
7.14
|
-6.08 |
3.21 |
|
VKPCPCVPKP |
8.81
|
-4.89 |
4.40 |
| Q07890 |
IPPPLPPRKK |
3.60
|
-9.84 |
-0.55 |
|
DPPAIPPRQP |
4.07
|
-9.55 |
-0.26 |
|
PAPPVPPRQN |
4.31
|
-8.89 |
0.40 |
| Q9UQC2 |
VYIPMSPGAH |
4.94
|
-6.65 |
2.64 |
|
PRPPKPSQAE |
5.44
|
-6.90 |
2.39 |
|
SEDNYVPMNP |
6.06
|
-6.73 |
2.56 |
| Q13905 |
PPFQLPLGGH |
4.23
|
-6.25 |
3.04 |
|
PPPALPPKKR |
4.93
|
-8.55 |
0.74 |
|
PKPPLPGIRV |
5.36
|
-8.15 |
1.14 |
| Q13480 |
SSPKTPPRRP |
4.97
|
-8.53 |
0.76 |
|
PRPPKPHPAH |
5.13
|
-7.67 |
1.62 |
|
NTYQIPRTFP |
5.58
|
-6.28 |
3.01 |
| P58107 |
PREPGPAGRG |
6.72
|
-5.75 |
3.54 |
|
QDAWRGPREP |
7.69
|
-6.53 |
2.76 |
|
QDARRGPREP |
8.15
|
-6.55 |
2.74 |
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