ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-9.PDB
Scoring matrix: BUD14_1CKA-9_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.18
Foldx random average score for Saccharomyces cerevisiae: 12.700

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1294554
Proteins after disorder filtering: 4390
 Total fragments: 56969
Proteins after pattern filtering: 2131
 Total fragments: 11393
Proteins after MINT filtering: 13
 Total fragments: 111


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.18

-0.60

0.00

Best peptides

RRPMFPRR

0.00

-3.62

-3.02

         
Interactors      
P13186

RPPIPAAL

8.23

-6.29

-5.69

IPLTPLAT

8.82

-3.49

-2.89

IPAALPPS

9.48

-3.63

-3.02

P27637

QPLSPPRE

8.83

-3.75

-3.15

YQPLSPPR

10.96

-5.68

-5.07

SPSTPIVE

12.11

-2.33

-1.73

Q12276

PQQLPSRK

7.69

-5.65

-5.04

LPSRKPKR

8.54

-5.66

-5.05

TRPKILPK

8.59

-3.14

-2.54

P38853

DLATPVTP

11.78

-3.70

-3.10

PTDTPTPR

12.22

-4.04

-3.44

TPVTPTSH

12.25

-3.44

-2.84

P40095

IPVLPPPR

6.42

-8.35

-7.74

PVLPPPRS

8.26

-3.99

-3.39

SPNRPTLS

8.75

-3.99

-3.39

P40036

LPTTPGIR

8.83

-6.54

-5.94

LPPLSPKS

9.21

-4.75

-4.14

PPLSPKST

11.37

-2.48

-1.88

P42073

RPPREPIE

10.05

-0.23

0.38

PREPIEFD

10.98

-2.29

-1.69

KRPPREPI

11.48

-2.33

-1.73

P53858

LPEFEPNR

9.97

-5.51

-4.90

PRVKPDSQ

10.16

-4.72

-4.12

PEFEPNRP

10.50

-4.28

-3.68

Q03016

PQQLPSRT

7.19

-4.60

-3.99

KPQTPILP

8.82

-5.93

-5.32

KPSRPSTS

8.84

-3.15

-2.54

Q07807

MMFMPPPP

6.53

-7.00

-6.39

FMPPPPLS

6.88

-3.87

-3.27

NTPVFRPS

9.88

-0.14

0.46

P40187

NPSPPIYK

10.33

-3.70

-3.10

PLNLPNNS

10.69

-4.24

-3.64

MDEPLNLP

11.81

-4.20

-3.60

P39960

NPATPNQK

8.78

-5.60

-4.99

KFFDPTLP

9.31

-5.94

-5.34

FDPTLPAS

10.74

-1.71

-1.11

P26570

EPKSPILK

9.77

-4.89

-4.29

PLNSPGLS

9.94

-2.66

-2.06

TPSKPNLE

9.94

-4.05

-3.44

 


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