ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-27.PDB
Scoring matrix: BUD14_1CKA-27_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 17.27
Foldx random average score for Saccharomyces cerevisiae: 16.276

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 2095758
Proteins after disorder filtering: 4742
 Total fragments: 148107
Proteins after pattern filtering: 2328
 Total fragments: 21913
Proteins after MINT filtering: 14
 Total fragments: 199


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

17.27

7.19

0.00

Best peptides

RDRRMHRFR

0.00

-0.30

-7.49

         
Interactors      
P13186

FKAPSYVPN

10.37

1.05

-6.14

RNSSIPMSP

11.24

-1.05

-8.24

PPIPAALPP

11.26

0.42

-6.77

P27637

MSDPASKPN

10.47

0.54

-6.65

QPLSPPREL

11.60

-0.50

-7.69

PLSPPRELD

12.93

1.75

-5.44

Q12276

LPSRKPKRG

7.95

-2.15

-9.34

GTRPKILPK

9.44

-0.49

-7.68

SDPPQQLPS

9.73

-0.12

-7.31

P38853

MDVPTDTPT

10.60

1.74

-5.45

SNKPFDTPT

11.76

2.30

-4.89

PVTPTSHQT

12.21

1.14

-6.05

P41818

PKTPYQGAV

14.87

3.29

-3.90

P40095

RSPNRPTLS

9.52

1.63

-5.56

PPPRSPNRP

9.91

-1.21

-8.40

LPPPRSPNR

10.44

1.74

-5.45

P40036

IELPPLSPK

11.40

1.15

-6.04

PTTPGIRSG

11.52

0.87

-6.32

KSLPTTPGI

12.61

3.16

-4.03

P42073

LNKRPPREP

7.18

-2.74

-9.93

RPPREPIEF

7.21

-2.70

-9.89

KRPPREPIE

8.68

0.76

-6.43

P53858

KEDPKPSPP

9.66

0.33

-6.86

LSTPRVKPD

9.68

-0.41

-7.60

KPSPPSSKL

10.03

0.93

-6.26

Q03016

KHPPISSPS

9.02

0.94

-6.25

LPSRTPKKG

9.32

-1.39

-8.58

SDPPQQLPS

9.73

-0.12

-7.31

Q07807

YPTPNPIPV

9.62

-0.26

-7.45

FMPPPPLSA

9.89

-0.22

-7.41

SPFPFAYPN

10.17

0.73

-6.46

P40187

MDEPLNLPN

9.05

-1.97

-9.16

NPSPPIYKK

10.12

0.13

-7.06

NGNPSPPIY

12.43

1.87

-5.32

P39960

FFDPTLPAS

12.11

2.99

-4.20

PATPNQKMR

12.47

-0.28

-7.47

INNPATPNQ

13.84

3.07

-4.12

P26570

WSDPTDSPN

10.13

1.21

-5.98

YSTPLNSPG

10.20

-0.34

-7.53

MEPKSPILK

12.24

-0.40

-7.59

 


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