ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-23.PDB
Scoring matrix: BUD14_1CKA-23_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.94
Foldx random average score for Saccharomyces cerevisiae: 11.829

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1407973
Proteins after disorder filtering: 4552
 Total fragments: 51688
Proteins after pattern filtering: 1879
 Total fragments: 7830
Proteins after MINT filtering: 13
 Total fragments: 69


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.94

-1.75

0.00

Best peptides

RPLFEWW

0.00

-5.23

-3.48

         
Interactors      
P13186

RPPIPAA

8.07

-4.25

-2.50

IPLTPLA

9.67

-5.85

-4.10

PPIPAAL

9.89

-4.32

-2.57

P27637

QPLSPPR

7.95

-5.79

-4.04

YQPLSPP

11.34

-3.95

-2.20

Q12276

RPKILPK

6.88

-5.15

-3.40

PSRKPKR

9.43

-4.37

-2.62

RRPSTTP

10.19

-3.37

-1.62

P38853

NKPFDTP

10.96

-4.61

-2.86

LATPVTP

11.50

-3.60

-1.85

P40095

PVLPPPR

9.20

-4.74

-2.99

RSPNRPT

9.69

-3.46

-1.71

NRIPVLP

10.09

-3.88

-2.13

P40036

KSLPTTP

8.68

-5.35

-3.60

LPPLSPK

9.53

-5.58

-3.83

PPLSPKS

9.89

-4.70

-2.95

P42073

RPPREPI

7.67

-3.65

-1.90

PPREPIE

9.69

-3.55

-1.80

KRPPREP

11.03

-4.40

-2.65

P53858

LPEFEPN

9.07

-4.52

-2.77

PNRPVSM

10.62

-3.53

-1.78

EDPKPSP

10.71

-4.09

-2.34

Q03016

IPLLTPI

7.20

-7.21

-5.46

KPQTPIL

9.76

-4.06

-2.31

PLLTPIN

10.33

-5.84

-4.09

Q07807

MFMPPPP

8.85

-5.46

-3.71

PFPFAYP

9.61

-6.11

-4.36

FMPPPPL

10.13

-3.18

-1.43

P40187

EPLNLPN

9.52

-5.54

-3.79

PSPPIYK

11.54

-3.51

-1.76

DEPLNLP

11.81

-4.59

-2.84

P39960

PTLPASN

10.59

-4.42

-2.67

P26570

MEPKSPI

8.82

-4.64

-2.89

TPLNSPG

10.45

-5.13

-3.38

EPKSPIL

10.80

-3.68

-1.93

 


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