ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-20.PDB
Scoring matrix: BUD14_1CKA-20_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.73
Foldx random average score for Saccharomyces cerevisiae: 15.861

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1425344
Proteins after disorder filtering: 4465
 Total fragments: 65120
Proteins after pattern filtering: 2078
 Total fragments: 8777
Proteins after MINT filtering: 14
 Total fragments: 82


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.73

-2.88

0.00

Best peptides

LRFFWGRWF

0.00

-7.11

-4.23

         
Interactors      
P13186

SSIPMSPNY

12.10

-6.25

-3.37

IPLTPLATN

14.73

-3.64

-0.76

EPLPEREPP

14.78

-5.66

-2.78

P27637

NMSDPASKP

14.09

-6.57

-3.69

PLSPPRELD

15.66

-7.11

-4.23

DYQPLSPPR

15.68

-6.45

-3.57

Q12276

RRPSTTPSH

11.59

-5.59

-2.71

PQQLPSRKP

13.04

-7.35

-4.47

FGRRPSTTP

13.14

-4.21

-1.33

P38853

NKPFDTPTI

10.92

-5.21

-2.33

LASAPSPAP

13.83

-6.06

-3.18

VMDVPTDTP

14.18

-5.69

-2.81

P41818

PKTPYQGAV

14.35

-6.38

-3.50

P40095

LPPPRSPNR

10.42

-8.35

-5.47

PRSPNRPTL

11.47

-7.92

-5.04

NRIPVLPPP

13.44

-6.74

-3.86

P40036

LPTTPGIRS

12.11

-5.51

-2.63

ELPPLSPKS

14.03

-6.67

-3.79

KSLPTTPGI

15.08

-6.39

-3.51

P42073

NKRPPREPI

11.74

-9.11

-6.23

PREPIEFDL

12.95

-4.90

-2.02

P53858

KPSPPSSKL

11.08

-7.76

-4.88

LKEDPKPSP

11.29

-7.01

-4.13

FLSTPRVKP

11.61

-4.23

-1.35

Q03016

KPSRPSTSP

12.18

-6.35

-3.47

LFSPANPKI

12.72

-7.50

-4.62

QLPSRTPKK

14.02

-5.89

-3.01

Q07807

YIYYPTPNP

10.16

-8.46

-5.58

PFAYPNPMM

11.83

-8.04

-5.16

NSPFPFAYP

12.32

-7.13

-4.25

P40187

NPSPPIYKK

14.64

-7.15

-4.27

ENGNPSPPI

14.96

-7.09

-4.21

P39960

NPATPNQKM

12.54

-6.25

-3.37

DPTLPASNS

14.97

-7.27

-4.39

INNPATPNQ

15.02

-4.05

-1.17

P26570

LWSDPTDSP

13.62

-5.15

-2.27

PLNSPGLSK

13.86

-4.92

-2.04

PKSPILKTN

14.14

-3.36

-0.48

 


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