Matrix information:
(Help) ADAN-name: 2B052.PDB Scoring matrix: 2B052_mat Uniprot code: P61981 Genome source: Homo sapiens Wild-type ligand: RAIsLP Foldx wt ligand score: 1.83 Foldx random average score for Homo sapiens: 10.129 Available information for P61981 in MINT (Nov 2008): Nš of interacting proteins: 204 Proteins belonging to other specie: 1 Nš of interactions described: 229 Interactions with other species: 2
Genome scanning information:
Subcellular location: False Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0 Proteins considered as fragments or having weird amino acids: 22829 Total scanned proteins: 48061 Total fragments: 22296734 Proteins after random average filtering: 48055 Total fragments: 12214885 Proteins after disorder filtering: 38081 Total fragments: 1382814 Proteins after pattern filtering: 3913 Total fragments: 4908 Proteins after MINT filtering: 30 Total fragments: 51 ROC parameters:
TPR= 0.147 FPR= 0.081 ACC= 0.916 SPC= 0.919 MCC= 0.016 Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
RAIsLP |
1.83
|
-15.22 |
0.00 |
Best peptides |
FPWEYW |
0.00
|
-10.89 |
4.33 |
|
|
|
|
|
Interactors |
|
|
|
|
Q7Z401 |
RLWSSP |
6.33
|
-10.22 |
5.00 |
|
RRSSLP |
8.15
|
-10.37 |
4.85 |
|
RPPSTG |
8.46
|
-8.98 |
6.24 |
Q9NYF8 |
RGDSKG |
7.18
|
-7.62 |
7.60 |
|
RDESRG |
7.46
|
-9.02 |
6.20 |
Q8N3F8 |
RGSSGP |
7.76
|
-6.44 |
8.78 |
|
RSGTRP |
9.30
|
-7.41 |
7.81 |
O75400 |
RRPSMG |
9.38
|
-9.67 |
5.55 |
Q86X29 |
RSSSAG |
8.22
|
-5.97 |
9.25 |
Q9ULJ3 |
RPQSQP |
6.57
|
-12.09 |
3.13 |
Q9Y2U5 |
RAQSYP |
4.38
|
-9.56 |
5.66 |
|
RDRSSP |
7.74
|
-7.88 |
7.34 |
Q6ZU52 |
RSPSAP |
9.32
|
-6.37 |
8.85 |
Q9UDY2 |
RLNSHG |
7.41
|
-8.04 |
7.18 |
O75044 |
RPSSQP |
7.09
|
-11.27 |
3.95 |
|
RSDSHG |
7.70
|
-7.65 |
7.57 |
Q15287 |
RSKSKP |
6.08
|
-10.13 |
5.09 |
|
RSASSG |
8.23
|
-6.93 |
8.29 |
Q96TC7 |
RSQSLP |
5.62
|
-10.92 |
4.30 |
Q92979 |
RERSGG |
7.81
|
-8.62 |
6.60 |
Q13627 |
RARSDP |
7.33
|
-8.68 |
6.54 |
P49761 |
RSPSFG |
8.64
|
-8.48 |
6.74 |
P49815 |
RSMSGG |
7.23
|
-8.52 |
6.70 |
O96013 |
RPLSGP |
6.33
|
-9.48 |
5.74 |
|
REGSGG |
8.75
|
-5.36 |
9.86 |
Q13009 |
RSSSTP |
7.34
|
-9.15 |
6.07 |
Q6W9G7 |
RTRSEP |
6.69
|
-10.33 |
4.89 |
|
RAQSSP |
7.11
|
-8.79 |
6.43 |
O75925 |
RTPSLP |
7.59
|
-10.08 |
5.14 |
O75494 |
RSWTSP |
8.34
|
-6.58 |
8.64 |
Q9H307 |
RSRSRG |
7.12
|
-8.96 |
6.26 |
Q9UQ35 |
RENSFG |
7.28
|
-8.46 |
6.76 |
|
RSNSSP |
8.11
|
-6.78 |
8.44 |
|
RSSSSP |
8.18
|
-7.21 |
8.01 |
P55196 |
RPKSEG |
5.99
|
-11.85 |
3.37 |
|
RPDSGG |
7.30
|
-8.99 |
6.23 |
|
RPASDG |
7.79
|
-9.06 |
6.16 |
Q99459 |
RTPSNG |
9.26
|
-8.21 |
7.01 |
|
RSGTTP |
9.29
|
-7.40 |
7.82 |
P10398 |
RGGSDG |
9.12
|
-6.52 |
8.70 |
P15056 |
RSSSAP |
7.84
|
-6.69 |
8.53 |
Q96SB4 |
RPLTRP |
7.45
|
-11.46 |
3.76 |
Q8IUD2 |
RTNSTG |
7.62
|
-9.10 |
6.12 |
P16471 |
RPGTDG |
10.07
|
-6.87 |
8.35 |
|