ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1R1Q2.PDB
Scoring matrix: 1R1Q2_mat
Uniprot code: O89100
Genome source: Mus musculus
Wild-type ligand: REyVNV
Foldx wt ligand score: 6.65
Foldx random average score for Mus musculus: 22.832

Available information for O89100 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 8
Nš of interactions described: 28
 Interactions with other species: 14

Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
 Total fragments: 20553348
Proteins after random average filtering: 44446
 Total fragments: 11565862
Proteins after disorder filtering: 34435
 Total fragments: 1166869
Proteins after pattern filtering: 16841
 Total fragments: 90031
Proteins after MINT filtering: 6
 Total fragments: 49


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

REyVNV

6.65

-18.93

0.00

Best peptides

DDyENL

0.00

-18.48

0.45

         
Interactors      
Q9QUN3

SDYENP

14.56

-9.78

9.15

DYENPD

17.39

-6.94

11.99

DSYEPP

19.18

-5.46

13.47

P70218

DDYDDV

12.30

-12.53

6.40

DDDYDD

14.24

-9.43

9.50

DYDDVD

15.88

-9.87

9.06

Q80U87

YPPEMA

21.44

-3.74

15.19

Q9Z1S8

DNYVPM

17.54

-9.29

9.64

DDNYVP

18.30

-3.68

15.25

ENYVPM

18.47

-7.77

11.16

O35601

EIYDGI

17.65

-8.54

10.39

DEIYDG

17.66

-6.86

12.07

YEEKPE

19.71

-4.09

14.84

Q9QYY0

LYTFNT

14.43

-8.98

9.95

DSSYCI

17.54

-4.36

14.57

ENYVPM

18.47

-7.77

11.16

 


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