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Matrix information:
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ADAN-name: 1AZG2.PDB
Scoring matrix: 1AZG2_mat
Uniprot code: P27986
Genome source: Homo sapiens
Wild-type ligand: PPRPLPVAPGSSKT
Foldx wt ligand score: 6.29
Foldx random average score for Homo sapiens: 9.716 Available information for P27986 in MINT (Nov 2008):
Nš of interacting proteins: 27
Proteins belonging to other specie: 5
Nš of interactions described: 83
Interactions with other species: 11
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 21912354
Proteins after random average filtering: 48017
Total fragments: 11762382
Proteins after disorder filtering: 33767
Total fragments: 915862
Proteins after pattern filtering: 24463
Total fragments: 348185
Proteins after MINT filtering: 13
Total fragments: 378
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PPRPLPVAPGSSKT |
6.29
|
-6.22 |
0.00 |
| Best peptides |
RRMGMPRMPKEGKR |
0.00
|
-5.18 |
1.04 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
TGPGLEGCPTNGPK |
6.20
|
-4.21 |
2.01 |
|
CDPSCPNGSCWGAG |
6.91
|
-3.36 |
2.86 |
|
NHLGSCQKCDPSCP |
7.35
|
-2.39 |
3.83 |
| P22681 |
KDKPLPVPPTLRDL |
4.35
|
-7.07 |
-0.85 |
|
SPLVGPECDHPKIK |
5.30
|
-3.08 |
3.14 |
|
SWLPRPIPKVPVSA |
5.45
|
-7.58 |
-1.36 |
| Q07666 |
VTRGVPPPPTVRGA |
4.84
|
-7.47 |
-1.25 |
|
QRIPLPPPPAPETY |
4.86
|
-6.51 |
-0.29 |
|
RQPPLPHRSRGGGG |
4.90
|
-6.18 |
0.04 |
| P35568 |
SLLGGPQGPGGMSA |
3.67
|
-4.08 |
2.14 |
|
GGPQGPGGMSAFTR |
5.59
|
-3.18 |
3.04 |
|
MSPGVAPVPSGRKG |
6.07
|
-4.46 |
1.76 |
| P42336 |
CDNVNTQRVPCSNP |
9.11
|
-3.29 |
2.93 |
| P10398 |
LTPQGPSPRTQHCD |
4.93
|
-4.88 |
1.34 |
|
TPRGSPSPASVSSG |
6.63
|
-4.77 |
1.45 |
|
EAPSNRPLNELLTP |
7.06
|
-5.92 |
0.30 |
| Q9UQC2 |
APPPRPPKPSQAET |
5.00
|
-7.63 |
-1.41 |
|
PRPPKPSQAETPRW |
5.69
|
-5.43 |
0.79 |
|
EDNYVPMNPGSSTL |
6.27
|
-4.17 |
2.05 |
| P29353 |
LGPILPPLPGDDSP |
4.45
|
-6.59 |
-0.37 |
|
VRKQMPPPPPCPGR |
5.12
|
-8.55 |
-2.33 |
|
ILPPLPGDDSPTTL |
5.62
|
-5.03 |
1.19 |
| P43405 |
NFGGRPQLPGSHPA |
6.00
|
-5.24 |
0.98 |
|
GRPQLPGSHPATWS |
6.79
|
-5.19 |
1.03 |
|
NVNFGGRPQLPGSH |
6.98
|
-1.31 |
4.91 |
| P04626 |
EDPTVPLPSETDGY |
5.67
|
-4.97 |
1.25 |
|
AAKGLQSLPTHDPS |
5.78
|
-6.01 |
0.21 |
|
PTVPLPSETDGYVA |
6.01
|
-4.41 |
1.81 |
| P21860 |
PVPIMPTAGTTPDE |
5.93
|
-5.16 |
1.06 |
|
PLHPVPIMPTAGTT |
6.18
|
-4.16 |
2.06 |
|
SGPGIAPGPEPHGL |
6.50
|
-3.75 |
2.47 |
| Q13480 |
PRPPKPHPAHDRSP |
4.77
|
-5.81 |
0.41 |
|
IPPPRPPKPHPAHD |
4.97
|
-7.35 |
-1.13 |
|
EDPVKPPGSSLQAP |
6.12
|
-5.88 |
0.34 |
| Q9Y5K6 |
PKMPGRRLPGRFNG |
4.66
|
-4.81 |
1.41 |
|
TVLAGPTSPIPSLG |
5.52
|
-3.93 |
2.29 |
|
PEKPVPPPPPIAKI |
5.53
|
-6.74 |
-0.52 |
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