ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1ABO2.PDB
Scoring matrix: 1ABO2_mat
Uniprot code: P00520
Genome source: Mus musculus
Wild-type ligand: APTMPPPLPP
Foldx wt ligand score: 3.09
Foldx random average score for Mus musculus: 11.953

Available information for P00520 in MINT (Nov 2008):
Nš of interacting proteins: 12
 Proteins belonging to other specie: 5
Nš of interactions described: 23
 Interactions with other species: 7

Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
 Total fragments: 20375566
Proteins after random average filtering: 44442
 Total fragments: 12012892
Proteins after disorder filtering: 32562
 Total fragments: 1259974
Proteins after pattern filtering: 23397
 Total fragments: 423366
Proteins after MINT filtering: 7
 Total fragments: 293


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

APTMPPPLPP

3.09

-13.57

0.00

Best peptides

MPRNKMMRIY

0.00

-12.79

0.78

         
Interactors      
Q06649

PPTSEPPPVP

4.56

-13.03

0.54

PPAYPPPPVP

4.89

-12.76

0.81

YPPAYPPPPV

5.37

-12.38

1.19

Q8CBW3

PPTQKPPSPP

3.12

-13.89

-0.32

APPPPPMPQL

5.60

-12.17

1.40

APGAAPGSQY

5.61

-9.55

4.02

O70469

VPGMRPGAPE

5.89

-11.42

2.15

PPPHLPDPLY

6.30

-10.85

2.72

MPTVLPRPES

6.34

-10.39

3.18

O35716

APVRPRPCPA

6.06

-11.10

2.47

AAPVRPRPCP

6.74

-9.12

4.45

CPAVPAPAPG

6.94

-9.78

3.79

P70429

PPPPPPPVPP

5.27

-14.15

-0.58

PPPPPPPPVP

5.46

-14.13

-0.56

PPPPPPVPPP

5.97

-13.37

0.20

P97814

SPKTTPSAPA

7.78

-9.00

4.57

STGREPPAPV

8.21

-9.77

3.80

PLIGSPSIQP

8.60

-7.59

5.98

P55194

APTMPPPLPP

3.09

-13.48

0.09

PPPALPPQPP

4.51

-12.62

0.95

MPPPLPPVPP

4.69

-13.89

-0.32

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER