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Matrix information:
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ADAN-name: 1A0N2.PDB
Scoring matrix: 1A0N2_mat
Uniprot code: P06241
Genome source: Homo sapiens
Wild-type ligand: PPRPLPVAPGSSK
Foldx wt ligand score: 5.44
Foldx random average score for Homo sapiens: 12.300 Available information for P06241 in MINT (Nov 2008):
Nš of interacting proteins: 29
Proteins belonging to other specie: 8
Nš of interactions described: 52
Interactions with other species: 15
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 21960385
Proteins after random average filtering: 48024
Total fragments: 11600588
Proteins after disorder filtering: 34459
Total fragments: 812271
Proteins after pattern filtering: 24595
Total fragments: 252318
Proteins after MINT filtering: 16
Total fragments: 325
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PPRPLPVAPGSSK |
5.44
|
-4.83 |
0.00 |
| Best peptides |
RHFGMPEMRGEWR |
0.00
|
-6.49 |
-1.66 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P54253 |
RVEGTAWLPGNPG |
6.43
|
-4.40 |
0.43 |
|
WLPGNPGGRGHGG |
6.59
|
-4.44 |
0.39 |
|
GTAWLPGNPGGRG |
7.21
|
-4.49 |
0.34 |
| P11137 |
SPMPSPFQGGSFT |
6.37
|
-4.88 |
-0.05 |
|
YSSRTPGTPGTPS |
6.44
|
-6.00 |
-1.17 |
|
SYPRTPHTPGTPK |
6.81
|
-6.47 |
-1.64 |
| O15117 |
KQKPLPPLFTLGP |
6.98
|
-5.42 |
-0.59 |
|
DLKPLGPKSGPTP |
6.99
|
-3.48 |
1.35 |
|
PPFLKPTGAGQRF |
7.58
|
-4.92 |
-0.09 |
| P22681 |
QRRPLPCTPGDCP |
4.90
|
-6.06 |
-1.23 |
|
HHHLSPHPPGTVD |
5.66
|
-3.67 |
1.16 |
|
LPFSLPSQMEPRP |
6.38
|
-6.43 |
-1.60 |
| Q07666 |
PPPPVPRGRGVGP |
7.99
|
-4.62 |
0.21 |
|
QRIPLPPPPAPET |
8.64
|
-5.79 |
-0.96 |
|
PPLPHRSRGGGGG |
8.98
|
-1.94 |
2.89 |
| Q13283 |
RDNRLRGPGGPRG |
8.08
|
-2.09 |
2.74 |
|
PGGPRGGLGGGMR |
8.32
|
-3.11 |
1.72 |
|
RRDNRLRGPGGPR |
8.90
|
-4.54 |
0.29 |
| P25445 |
QFCHKPCPPGERK |
7.69
|
-5.63 |
-0.80 |
|
CHKPCPPGERKAR |
10.35
|
-2.50 |
2.33 |
|
DCTVNGDEPDCVP |
11.46
|
-1.38 |
3.45 |
| Q13444 |
PRKPLPADPQGRC |
7.08
|
-6.43 |
-1.60 |
|
GPSERPGPPQRAL |
8.03
|
-3.92 |
0.91 |
|
SERPGPPQRALLA |
8.29
|
-3.22 |
1.61 |
| P42768 |
NQLPRPPIVGGNK |
6.18
|
-6.22 |
-1.39 |
|
RRGGLPPLPLHPG |
7.19
|
-6.84 |
-2.01 |
|
GLPPLPLHPGGDQ |
7.41
|
-5.26 |
-0.43 |
| P16333 |
KVKRKPSVPDSAS |
7.47
|
-7.46 |
-2.63 |
|
GLEPSPPQCDYIR |
9.93
|
-2.93 |
1.90 |
|
KRKPSVPDSASPA |
10.26
|
-1.60 |
3.23 |
| Q9Y5K6 |
PKMPGRRLPGRFN |
7.08
|
-4.48 |
0.35 |
|
PKKPTPPTKASNL |
7.81
|
-4.25 |
0.58 |
|
RSSGTVYPKRPEK |
9.39
|
-2.70 |
2.13 |
| P29353 |
LGPILPPLPGDDS |
5.38
|
-6.11 |
-1.28 |
|
AGPPNPAINGSAP |
7.20
|
-3.97 |
0.86 |
|
NDFPGKEPPLGGV |
9.11
|
-4.48 |
0.35 |
| P12931 |
PASQTPSKPASAD |
9.60
|
-3.60 |
1.23 |
|
GAFPASQTPSKPA |
10.34
|
-2.11 |
2.72 |
|
SQTPSKPASADGH |
11.32
|
-1.10 |
3.73 |
| P06729 |
APSHRPPPPGHRV |
6.46
|
-6.32 |
-1.49 |
|
HQQKGPPLPRPRV |
8.78
|
-4.83 |
0.00 |
|
RPRVQPKPPHGAA |
9.15
|
-4.65 |
0.18 |
| P35968 |
GPQPLPIHVGELP |
8.84
|
-3.63 |
1.20 |
| Q13177 |
ANHSLKPLPSVPE |
8.03
|
-5.90 |
-1.07 |
|
DKPPAPPVRMSST |
8.69
|
-3.64 |
1.19 |
|
PPEKDGFPSGTPA |
11.32
|
0.79 |
5.62 |
|
